HLA-B27 Testing
20th October 2025
Further to communications last month we have continued to experience supply chain issues. We are now changing our methodology to one that requires DNA extraction prior to testing for HLA-B27.
Due to this change we will be restricting the tube types that we can receive; any others received are likely to result in a request being cancelled. Sample tubes can be part filled if you have a patient that is difficult to bleed.
Allowed tube types are:
BD 3ml, 4ml, 6ml
Sarstedt 2.6ml, 3.4ml, 4.9ml
Greiner Bio-One 3ml, 4ml, 6ml
Please share this information with your phlebotomy colleagues.
During this period of change you may notice some delay to issuing of results; please bear with us and escalate any urgent requests or questions to us via email tissue.typing@nhs.net.